GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9815354 | 1 | rs6803560 | chr3:41824480 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.72 | 4.23E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs6803652 | chr3:41824556 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.72 | 4.23E-20 | Diastolic blood pressure |
| BLCA | cis | rs1401999 | 1 | rs6804242 | chr3:183659463 | ABCC5 | chr3:183637726-183735727:- | -0.2 | -3.88 | 0.000123 | Anterior chamber depth |
| BLCA | cis | rs1401999 | 1 | rs6804242 | chr3:183659463 | VWA5B2 | chr3:183948317-183960116:+ | -0.26 | -4.16 | 3.94E-5 | Anterior chamber depth |
| BLCA | cis | rs10935120 | 1 | rs6804770 | chr3:134230234 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.99 | 1.6E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs6804770 | chr3:134230234 | CEP63 | chr3:134204575-134293852:+ | 0.24 | 4.2 | 3.36E-5 | Height |
| BLCA | cis | rs6805251 | 1 | rs6805251 | chr3:119560606 | KTELC1 | chr3:119187785-119213552:+ | -0.23 | -4.03 | 6.73E-5 | HDL cholesterol |
| BLCA | cis | rs9815354 | 1 | rs6805880 | chr3:41865397 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.66 | 6.48E-20 | Diastolic blood pressure |
| BLCA | cis | rs1401999 | 1 | rs6805913 | chr3:183662924 | VWA5B2 | chr3:183948317-183960116:+ | -0.25 | -3.96 | 9.11E-5 | Anterior chamber depth |
| BLCA | cis | rs10935120 | 1 | rs6806417 | chr3:134211446 | ANAPC13 | chr3:134196547-134204865:- | -0.49 | -7.88 | 3.34E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs6806417 | chr3:134211446 | CEP63 | chr3:134204575-134293852:+ | -0.23 | -4.03 | 6.72E-5 | Height |
| BLCA | cis | rs9815354 | 1 | rs6807015 | chr3:41754514 | ULK4 | chr3:41288091-42003660:- | 0.66 | 10.08 | 2.35E-21 | Diastolic blood pressure |
| BLCA | cis | rs853679 | 1 | rs68141011 | chr6:28217797 | ZNF389 | chr6:28129551-28137375:+ | -0.33 | -4.07 | 5.63E-5 | Depression |
| BLCA | cis | rs1577917 | 1 | rs68171315 | chr6:86707400 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -9.13 | 4.02E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs68189316 | chr7:65409169 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.47 | 1.02E-5 | Diabetic kidney disease |